Clinical Research Directory

Inclusion Criteria: * Children and adolescents aged 3-11 years old * Clinical diagnosis of ASD, based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) * Associated with gastrointestinal symptoms for at least 14 days (diarrhea, constipation, abdominal pain, bloating and/or food allergies/intolerances) * With guardians who can fully understand the informed consent and voluntarily sign the written informed consent Exclusion Criteria: * Antibiotics or probiotics used within 1 mont * Serious gastrointestinal problems that require immediate treatment (such as life-threatening intestinal obstruction, intestinal perforation, intestinal bleeding * Medications related to mental disorders or depression * Relying on tube feeding * Swallowing dysfunction that unable to take capsules * History of severe allergies * Paticipation in other clinical studies within 4 weeks * Poor compliance and have difficulty in completing follow-up.