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RECRUITING
NCT06421519
PHASE1/PHASE2

Different Levels of BiPAP

Sponsor: King's College Hospital NHS Trust

View on ClinicalTrials.gov

Summary

Some infants with breathing problems at birth may need to be connected to a machine to help support their breathing. The purpose of this study is to optimise the level of breathing support on Bi level continuous airway pressure (BiPAP), a support which gives two levels of support (pressure) to premature infants. The study is investigating which upper pressure gives the best support, that is results in the baby having to breathe less hard (work of breathing). Researchers will measure the work of breathing using a small catheter. Infants will receive three different upper pressures of BiPAP with the same baseline pressure for 20 minutes each. In between each upper level they will receive the standard upper pressure for 20 minutes.

Official title: Crossover Study of the Work of Breathing at Different Levels of BiPAP Settings in Neonates

Key Details

Gender

All

Age Range

2 Days - 2 Months

Study Type

INTERVENTIONAL

Enrollment

21

Start Date

2024-05-23

Completion Date

2024-08-01

Last Updated

2024-06-11

Healthy Volunteers

No

Interventions

OTHER

BiPAP setting

Infants in this arm of the study will each rotate through three different BiPAP settings. The following BiPAP settings will be used: 13cmH2O / 5cmH2O, 10cmH2O / 5cmH2O, 7cmH2O / 5cmH2O

Locations (1)

King's College Hospital

London, United Kingdom