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Different Levels of BiPAP
Sponsor: King's College Hospital NHS Trust
Summary
Some infants with breathing problems at birth may need to be connected to a machine to help support their breathing. The purpose of this study is to optimise the level of breathing support on Bi level continuous airway pressure (BiPAP), a support which gives two levels of support (pressure) to premature infants. The study is investigating which upper pressure gives the best support, that is results in the baby having to breathe less hard (work of breathing). Researchers will measure the work of breathing using a small catheter. Infants will receive three different upper pressures of BiPAP with the same baseline pressure for 20 minutes each. In between each upper level they will receive the standard upper pressure for 20 minutes.
Official title: Crossover Study of the Work of Breathing at Different Levels of BiPAP Settings in Neonates
Key Details
Gender
All
Age Range
2 Days - 2 Months
Study Type
INTERVENTIONAL
Enrollment
21
Start Date
2024-05-23
Completion Date
2024-08-01
Last Updated
2024-06-11
Healthy Volunteers
No
Conditions
Interventions
BiPAP setting
Infants in this arm of the study will each rotate through three different BiPAP settings. The following BiPAP settings will be used: 13cmH2O / 5cmH2O, 10cmH2O / 5cmH2O, 7cmH2O / 5cmH2O
Locations (1)
King's College Hospital
London, United Kingdom