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RECRUITING
NCT06423131
NA

Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCT

Sponsor: Sijia Gu

View on ClinicalTrials.gov

Summary

This is a single-center prospective, non-randomized controlled clinical study in China using CliniMACS TCRα/β+ cell depleted stem cell haploidentical donors versus conventional Beijing protocol for haploidentical hematopoietic stem cell transplantation in children.

Official title: TCRαβ+ Cell Deleted Versus Traditional Haploidentical Hematopoietic Stem Cell Transplantation :A Single-center, Prospective, Non-randomized Controlled Clinical Study

Key Details

Gender

All

Age Range

8 Weeks - 18 Years

Study Type

INTERVENTIONAL

Enrollment

110

Start Date

2024-05-26

Completion Date

2028-03-31

Last Updated

2024-05-29

Healthy Volunteers

No

Interventions

PROCEDURE

TCRαβ Depleted haploidentical HCT

Use the CliniMACS TCRα/β deplete from the mobilized peripheral blood stem cells of haploidentical donor in children

Locations (1)

Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, China