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Exploration of Mechanisms for Weaning Failure
Sponsor: The First Affiliated Hospital of Guangzhou Medical University
Summary
This study is a prospective physiologic study. The primary study population will be adult invasive tracheal intubated patients with COPD, and investigators will collect relevant demographic data, vital signs, and baseline physiologic parameters of the patients prior to the spontaneous breathing test（SBT). The participants will be divided into a successful withdrawal group and a failed withdrawal group according to the SBT outcome, and the changes in the above parameters during SBT will be compared between the two groups .
Official title: Changes in Respiratory Mechanics in Patients With Failed Ventilator Withdrawal
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2024-07-09
Completion Date
2025-12-01
Last Updated
2024-07-09
Healthy Volunteers
Yes
Interventions
Monitoring of respiratory mechanics parameters
Physiologic recording instrumentation measure maximal transdiaphragmatic pressure，twitch diaphragmatic pressure and maximal diaphragmatic electromyography
Locations (1)
The First Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China