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Fish Oil, Metformin and Heart Health in PCOS
Sponsor: University of Alberta
Summary
Women with Polycystic Ovary Syndrome (PCOS) have high testosterone levels which is associated with altered insulin-glucose metabolism and an adverse blood lipid profile, predisposing them to the development of Type II Diabetes and Cardiovascular Disease (CVD). This study will investigate the use of dietary fish oil supplementation as a safe and effective intervention, and as an adjunct therapy to standard of care treatment with metformin to improve heart health, blood lipids and insulin-glucose metabolism in women with PCOS, and those with PCOS and Type 2 Diabetes.
Official title: Dietary Fish Oil and Metformin Intervention for Heart Health in PCOS
Key Details
Gender
FEMALE
Age Range
25 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
146
Start Date
2025-11-01
Completion Date
2027-12-30
Last Updated
2025-12-12
Healthy Volunteers
No
Conditions
Interventions
Fish oil
For 12 months
Metformin
12 months
Fish Oil and Metformin
12 months
Locations (3)
Human Nutrition Research Unit - Li Ka Shing Health Research Center
Edmonton, Alberta, Canada
Mazankowski Alberta Heart Institute
Edmonton, Alberta, Canada
University of Alberta Hospital - Division of Endocrinology
Edmonton, Alberta, Canada