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Clinical Outcome in Patients With INPH
Sponsor: Xuanwu Hospital, Beijing
Summary
The aim of this study is to determine the clinical spectrum and natural progression of idiopathic normal pressure hydrocephalus (iNPH ) and related disorders in a prospective single center study, identify digital, imaging and molecular biomarkers that can assist in diagnosis and therapy development and study the etiology and molecular mechanisms of these diseases.
Official title: Phenotypes, Biomarkers and Pathophysiology in INPH
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2024-05-15
Completion Date
2027-05
Last Updated
2024-05-24
Healthy Volunteers
Yes
Interventions
hydrocephalus group
Diagnostic Test: high throughput sequencing and electromyography Whole Genome Sequencing, Whole Exome Sequencing, Transcriptomics, Proteomics, Metabolomics and imaging, such as DTIALPS
normal group
Whole Genome Sequencing, Whole Exome Sequencing, Transcriptomics, Proteomics, Metabolomics and imaging, such as DTIALPS
Locations (1)
Fengzeng Jian
Beijing, Beijing Municipality, China