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RECRUITING
NCT06429150
PHASE1/PHASE2

Frontline Combination CAR-T Cell Therapy for Multiple Myeloma or Plasmacytoma

Sponsor: Shenzhen Geno-Immune Medical Institute

View on ClinicalTrials.gov

Summary

The aim of this clinical trial is to assess the feasibility, safety, and efficacy of CAR-T cell therapy targeting multiple cancer cell antigens in high-risk multiple myeloma or plasmacytoma as part of a frontline treatment regimen for patients. Another goal of the study is to learn more about the persistence and function of these CAR-T cells in the body.

Official title: Frontline Management of High-Risk Multiple Myeloma or Plasmacytoma With BCMA and GPRC5D Combination CAR-T Cell Therapy

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2024-05-11

Completion Date

2027-12-31

Last Updated

2024-06-10

Healthy Volunteers

No

Interventions

BIOLOGICAL

CAR-T cells

Infusion of multi-CAR-T cells

Locations (2)

Shenzhen Geno-immune Medical Institute

Shenzhen, Guangdong, China

Hematologist of the Regional Hematology Center in Clinical Hospital No. 2 of the Ministry of Health

Vladivostok, Russia