Clinical Research Directory
Browse clinical research sites, groups, and studies.
Liposomal Bupivacaine vs Ropivacaine for TAPBs
Sponsor: Sun Yat-sen University
Summary
Few studies have compared the efficacy of ultrasound (US)-guided TAP blocks with Liposomal bupivacaine(LB) versus ropivacaine in reducing postoperative opioid usage in patients undergoing laparoscopic lower abdominal tumor Resection. Therefore, we are conducting this prospective, randomized controlled trial to compare the postoperative analgesic effects of LB and ropivacaine for TAP blocks among patients undergoing laparoscopic colorectal procedures.
Official title: Liposomal Bupivacaine vs Ropivacaine for Ultrasound-guided Transversus Abdominis Plane Blocks in Laparoscopic Lower Abdominal Tumor Resection: A Prospective Randomized Trial
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
74
Start Date
2023-11-01
Completion Date
2024-06
Last Updated
2024-05-28
Healthy Volunteers
No
Interventions
Liposomal Bupivacaine
After induction of anesthesia, bilateral TAPB was performed under ultrasound guidance. The patients in the bupivacaine liposome group were injected with bupivacaine liposome 133mg(10ml+ 10ml 0.9% normal saline mixed into 20ml)/ point (two points in total).
Ropivacaine
Patients in ropivacaine group were given 0.25% ropivacaine 20ml/ point (two points in total).
Locations (1)
Jingdun Xie
Guangzhou, Guangdong, China