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Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma
Sponsor: University Hospital, Bordeaux
Summary
Glioblastomas are the most frequent and aggressive malignant tumors of the CNS in adults, with almost systematic relapse despite treatment with surgery followed by radio-chemotherapy (STUPP protocol). The aim of this study is to better characterize transcriptomic, proteomic and metabolic changes in relapsed glioblastoma compared to the initial tumor, in order to identify new prognostic markers and potential new therapeutic targets.
Official title: Study of Metabolic, Genomic and Proteomic Modifications in Relapsed Glioblastoma. Identification or Prognostic Markers in Patients Undergoing Surgery for Relapsed Glioblastoma.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
40
Start Date
2024-04-05
Completion Date
2026-04
Last Updated
2025-07-30
Healthy Volunteers
No
Interventions
Relapsed glioblastoma
Paired tumor samples diagnosis/relapse
Locations (1)
CHU de Bordeaux - Hôpital Saint-André, Service d'Oncologie Médicale
Bordeaux, France