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RECRUITING
NCT06430424

Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma

Sponsor: University Hospital, Bordeaux

View on ClinicalTrials.gov

Summary

Glioblastomas are the most frequent and aggressive malignant tumors of the CNS in adults, with almost systematic relapse despite treatment with surgery followed by radio-chemotherapy (STUPP protocol). The aim of this study is to better characterize transcriptomic, proteomic and metabolic changes in relapsed glioblastoma compared to the initial tumor, in order to identify new prognostic markers and potential new therapeutic targets.

Official title: Study of Metabolic, Genomic and Proteomic Modifications in Relapsed Glioblastoma. Identification or Prognostic Markers in Patients Undergoing Surgery for Relapsed Glioblastoma.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

40

Start Date

2024-04-05

Completion Date

2026-04

Last Updated

2025-07-30

Healthy Volunteers

No

Interventions

BIOLOGICAL

Relapsed glioblastoma

Paired tumor samples diagnosis/relapse

Locations (1)

CHU de Bordeaux - Hôpital Saint-André, Service d'Oncologie Médicale

Bordeaux, France