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Hyaluronic Acid Delivery: CO2 Laser Versus Thulium Laser Treatment
Sponsor: Universitätsklinikum Hamburg-Eppendorf
Summary
* Weakly crossed-linked hyaluronic acid (HA) can be delivered through multiple injections into the dermal and subnormal layer to improve skin quality. However, this treatment comes with multiple bumps for several days. * Alternatively, HA can be delivered after CO2 laser or thulium laser pretreatment. As microscopic analysis after this treatment is limited, the object of the present study is to investigate the morphological cellular changes after CO2 laser and thulium laser delivered HA into human skin.
Official title: In Vivo Visualisation of Hyaluronic Acid After CO2 Laser Compared to Thulium Laser Treatment
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-02-20
Completion Date
2024-06-30
Last Updated
2024-05-28
Healthy Volunteers
Yes
Conditions
Interventions
CO2 laser + HA
Probands will be treated with a CO2 laser. Afterwards a HA gel will be applied. To measure microscopic cellular changes, a multiphoton tomography will be used.
Thulium laser + HA
Probands will be treated with a thulium laser. Afterwards a HA gel will be applied. To measure microscopic cellular changes, a multiphoton tomography will be used.
Locations (1)
University Medical-Center Hamburg-Eppendorf
Hamburg, Germany