Clinical Research Directory

A Model for Drug Concentration Prediction of Vancomycin

Sponsor: Peking Union Medical College Hospital

Summary

Objective: This study aims to use machine learning methods to establish an optimal model for predicting serum vancomycin trough concentrations in critically ill patients. Methods: This is a single-center, retrospective study. Data on serum vancomycin concentration in the Critical Care Database of Peking Union Medical College Hospital were screened and extracted to construct a prediction model using machine learning methods. The MIMIC-IV (Medical Information Mart for Intensive Care) database will be further used for external verification of the constructed model. The study has been approved by the Medical Ethics Committee of Peking Union Medical College Hospital (K24C1161).

Official title: A Clinical Data-Based Model for Drug Concentration Prediction of Vancomycin in Critical Patients

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