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Recurrent Campylobacter Bacteraemia in Immunocompromised Patients
Sponsor: Hospices Civils de Lyon
Summary
Some rare cases of recurrent Campylobacter bacteraemia (RCB) exist with relapses months to years after an effective treatment and a negativation of all bacterial samples. As of today, only around 20 cases have been described in the international literature for the last 30 years. The cases are likely highly underreported. No study describes those recurrent Campylobacter bacteraemias at the scale of a country. The aim of this multicentre, nationwide, retrospective study is to describe their precise epidemiology in France for the last 25 years, the immune profile of the patients, the specificities of the bacteria involved, the treatments received and the evolution of these infections. The perspective is to propose a standardization of the medical care of those patients mainly by describing the effective treatments and the explorations of the immune system which should be considered.
Official title: Recurrent Campylobacter Bacteraemia in Immunocompromised Patients: a Retrospective Nationwide Study in France, 2000-2025
Key Details
Gender
All
Age Range
Any - 100 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2024-06-01
Completion Date
2026-05-01
Last Updated
2024-05-29
Healthy Volunteers
No
Conditions
Interventions
Characteristics of patients and Campylobacter bacteraemia episodes
Variables: characteristics of the patients (demographic characteristics; characteristics of immunodeficiency: diagnosis, immunoglobulin dosage, white cells count etc.; chronic inflammatory bowel disease \[IBD\]), the bacteria (species, antimicrobial susceptibility) and the infection (clinical presentation, evolution, treatment received)
Locations (1)
Infectious diseases department, Hospital de la Croix Rousse,
Lyon, France