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Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells
Sponsor: Shenzhen Geno-Immune Medical Institute
Summary
The purpose of this study is to assess the feasibility, safety and efficacy of mesenchymal stem cells (MSCs) in combination with CAR-T cells in treating autoimmune disease. Another goal of the study is to learn more about the safety and function of the MSCs combined with CAR-T cells and their long term effects in autoimmune disease patients.
Official title: Management of Autoimmune Conditions With Mesenchymal Stem Cells (MSCs) and CAR-T Cells
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-05-15
Completion Date
2027-12-31
Last Updated
2024-05-30
Healthy Volunteers
No
Conditions
Interventions
fetal MSCs combined with 4SCAR T cells
Infusion of 4SCAR T cells at 10\^6 cells/kg body weight and MSCs at 3x10\^6 cells via IV
Locations (1)
Shenzhen Geno-immune Medical Institute
Shenzhen, Guangdong, China