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Rebuilding Inter-limb Transfer in Cervical SCI
Sponsor: The Cleveland Clinic
Summary
The purpose of this study in people living with cervical Spinal Cord Injury (SCI) is to examine the effects of paired neurostimulation (i.e., PCMS) combined with contralateral motor training on inter-limb transfer of ballistic motor and hand dexterity skills.
Official title: Improving Upper Limb Rehabilitation by Rebuilding Inter-limb Transfer of Motor Gains in Cervical SCI
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
17
Start Date
2024-02-15
Completion Date
2026-07-30
Last Updated
2026-03-24
Healthy Volunteers
Yes
Conditions
Interventions
PCMS + Contralateral Motor Training
PCMS + Contralateral Motor Training will involve delivering 360 pairs of TMS-PNS pulses (30min, 0.2 Hz) to the weaker first dorsal interosseous (FDI) muscle immediately before a session of ballistic index finger abduction training at the opposite, stronger FDI muscle.
PCMS + Rest
PCMS + Rest will involve delivering 360 pairs of TMS-PNS pulses (30min, 0.2Hz) to the weaker FDI followed by a 30-min rest.
Sham PCMS + Contralateral Motor Training
360 TMS pulses will be delivered at a location 10-cm posterior to the participant's head (into the air, 0.2Hz) and no PNS pulses will be generated, followed by a session of 30-min ballistic index finger abduction training at the opposite, stronger FDI muscle.
Locations (1)
Lerner Research Institute; Cleveland Clinid Foundation
Cleveland, Ohio, United States