Clinical Research Directory

Inclusion Criteria: * Men or women of ≥18 year old; * Hospitalized between Jan 1, 2016 and Aug. 1, 2023; * Received intravenous (IV) Xueshuantong (lyophilized) for ≥3 days; * Who also meet one of the following criteria: 1. Perioperative patients: Performed any of the following surgical procedures (≥ 45 minutes in duration) during hospitalization- general surgery, orthopedic surgery, obstetrics and gynecology surgery, neurosurgery, urology surgery, cardiothoracic surgery, obesity surgery or cancer surgery; 2. Hospitalization due to acute spontaneous cerebral hemorrhage: Diagnosed as cerebral hemorrhage (acute/subacute), or subarachnoid hemorrhage, with clinical manifestations such as conscious disturbance, dyskinesia, or sensory dysfunction. Presence of cerebral hemorrhage was confirmed by imaging; 3. Hospitalization due to acute ischemic stroke: Diagnosed as ischemic stroke, ischemic stroke (acute/subacute), cerebral infarction, or cerebral infarction (acute/subacute), acute stage or subacute stage of ischemic stroke, with clinical manifestations such as disturbance of consciousness, motor dysfunction, or sensory dysfunction. Presence of cerebral hemorrhage was confirmed by imaging. Exclusion Criteria: * Received any traditional Chinese medicine (TCM) that contains total saponins of panax notoginseseng (PNS) other than Xueshuantong (lyophilized); * Females who are pregnant or breast-feeding; * Diagnosed venous thromboembolism occurred before enrollment; * Received intravenous thrombolytic therapy for other reasons during hospitalization; * Received prophylactic or therapeutic doses of anticoagulants after major surgery; * Placed vena cava filters for VTE prophylaxis before surgery; * Received therapeutic dose of anticoagulants during the patient's hospital stay (AIS patients);