Clinical Research Directory
Browse clinical research sites, groups, and studies.
Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia
Sponsor: Mongi Slim Hospital
Summary
A prospective, bicentric, randomized, double-blind controlled study including parturients scheduled for elective caesarean delivery under spinal anaesthesia and randomized and assigned to one of the two groups: Group O ondansetron : receiving Intravenous (IV) ondansetron 0.10 mg/ kg diluted in 5 ml normal saline, 5 min before spinal anesthesia Group C control : receiving IV normal saline 5 ml (control group) 5 min before spinal anesthesia OBJECTIVE : To evaluate the efficacy of ondansetron in preventing post-dural puncture headache after spinal anaesthesia for caesarean section.
Official title: Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia for Cesarean Sections : A Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2023-11-30
Completion Date
2024-08-30
Last Updated
2024-06-06
Healthy Volunteers
No
Conditions
Interventions
Intravenous ondansetron
Intravenous (IV) ondansetron 0.10 mg/ kg diluted in 5 ml normal saline, 5 min before spinal anesthesia
Intravenous normal saline
Intravenous normal saline 5 ml (control group) 5 min before spinal anesthesia
Locations (1)
Mongi slim hospital
Tunis, Tunisia