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RECRUITING
NCT06446453
NA

Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure

Sponsor: Connecticut Children's Medical Center

View on ClinicalTrials.gov

Summary

Point-of-care ultrasound (POCUS) is the use of ultrasound by the bedside provider in real time to answer a specific question and guide medical management. POCUS can be used to diagnose the severity of neonatal respiratory distress syndrome (RDS) through a lung ultrasound score. Lung ultrasound scores have also been shown to predict if an infant is treated with an initial dose of surfactant. Therefore, using lung ultrasound scores to guide surfactant therapy for RDS will likely lead to earlier surfactant therapy and may improve short-term respiratory outcomes. This study will test this theory by comparing lung ultrasound score-guided surfactant therapy for premature infants with RDS with our current surfactant administration guidelines.

Key Details

Gender

All

Age Range

0 Hours - 2 Hours

Study Type

INTERVENTIONAL

Enrollment

52

Start Date

2024-06-25

Completion Date

2026-06

Last Updated

2025-06-05

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Echography-guided Surfactant THERapy (ESTHER)

Decision to administer surfactant therapy using a semi-quantitative lung ultrasound score.

Locations (1)

Connecticut Children's

Hartford, Connecticut, United States