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Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure
Sponsor: Connecticut Children's Medical Center
Summary
Point-of-care ultrasound (POCUS) is the use of ultrasound by the bedside provider in real time to answer a specific question and guide medical management. POCUS can be used to diagnose the severity of neonatal respiratory distress syndrome (RDS) through a lung ultrasound score. Lung ultrasound scores have also been shown to predict if an infant is treated with an initial dose of surfactant. Therefore, using lung ultrasound scores to guide surfactant therapy for RDS will likely lead to earlier surfactant therapy and may improve short-term respiratory outcomes. This study will test this theory by comparing lung ultrasound score-guided surfactant therapy for premature infants with RDS with our current surfactant administration guidelines.
Key Details
Gender
All
Age Range
0 Hours - 2 Hours
Study Type
INTERVENTIONAL
Enrollment
52
Start Date
2024-06-25
Completion Date
2026-06
Last Updated
2025-06-05
Healthy Volunteers
No
Interventions
Echography-guided Surfactant THERapy (ESTHER)
Decision to administer surfactant therapy using a semi-quantitative lung ultrasound score.
Locations (1)
Connecticut Children's
Hartford, Connecticut, United States