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Trial of Precision Medicine in Emergency Departments
Sponsor: University of Florida
Summary
The objectives of this study are to (1) test the feasibility of the clinical implementation of preemptive pharmacogenetic (PGx) testing in the emergency department (ED) and (2) determine if PGx testing (with appropriate decision support) decreases ED return visits and hospitalizations. We will conduct a randomized, controlled, pragmatic clinical trial assessing both the real-world effectiveness as well as implementation outcomes using a targeted PGx testing panel in several UF Health EDs.
Key Details
Gender
All
Age Range
40 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1200
Start Date
2025-03-18
Completion Date
2029-02-01
Last Updated
2025-05-11
Healthy Volunteers
Yes
Conditions
Interventions
Panel-based pharmacogenetic genotyping
After consent and randomization into the immediate PGx testing, participants' results will (10-14 days after randomization) go into their EHR and be returned via a laminated results card
Locations (3)
UF Health Emergency Department
Gainesville, Florida, United States
UF Health Jacksonville Downtown Emergency Department
Jacksonville, Florida, United States
UF Health Jacksonville North Emergency Department
Jacksonville, Florida, United States