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RECRUITING
NCT06448403

Multimodal Assesment of Alzheimer Patients

Sponsor: Norwegian University of Science and Technology

View on ClinicalTrials.gov

Summary

The goal of this study is to learn more about the changes in the brains of patients with cognitive impairment (MCI) and Alzheimer's Disease (AD). The main questions the study aims to answer are: 1. What findings can be used to earlier detect patients that will develop Alzheimers? 2. Which differences are seen between healthy and cognitively impaired patients? 3. Which differences are seen between patients with Alzheimers disease? Participants will undergo: * Cognitive tests * Magnetic resonance imaging (MRI) * Electroencephalography (EEG) * Blood sample collection * Fecal sample collection * A randomized group will undergo polysomnography analysis.

Official title: Multimodal Assessment of Cognitive Impairment in Alzheimer Patients

Key Details

Gender

All

Age Range

65 Years - Any

Study Type

OBSERVATIONAL

Enrollment

60

Start Date

2024-07-01

Completion Date

2030-12-29

Last Updated

2025-08-07

Healthy Volunteers

Yes

Interventions

DEVICE

MRI Scanning

MRI scanning with volumetric, resting and activity-based sequences.

DEVICE

64-channel EEG

EEG to quantifiy electric activity.

DEVICE

Polysomnography

A randomized group will undergo polysomnography.

BIOLOGICAL

Blood samples

Analysis of specific blood biomarkers.

BIOLOGICAL

Fecal samples

Analysis of bacterial composition.

BEHAVIORAL

Cognitive tests

Interview-based cognitive tests for assesment of cognitive levels.

Locations (1)

Norwegian University of Sciene and Technology / Norges teknisk-naturvitenskapelige universitet (NTNU)

Trondheim, Trønderlag, Norway