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The PICM Risk Prediction Study - Application of AI to Pacing
Sponsor: Guy's and St Thomas' NHS Foundation Trust
Summary
Development of pacing induced cardiomyopathy (PICM) is correlated to a high morbidity as signified by an increase in heart failure admissions and mortality. At present a lack of data leads to a failure to identify patients who are at risk of PICM and would benefit from pre-selection to physiological pacing. In the light of the foregoing, there is an urgent need for novel non-invasive detection techniques which would aid risk stratification, offer a better understanding of the prevalence and incidence of PICM in individuals with pacing devices and the contribution of additional risk factors.
Official title: Predictive Risk Algorithm for Development of Right Ventricular Pacing Induced Cardiomyopathy - a Step Towards Personalized Pacemaker Lead Deployment
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
10000
Start Date
2024-07-30
Completion Date
2026-10-30
Last Updated
2024-06-07
Healthy Volunteers
No
Interventions
Machine learning
Analysis of data with machine learning methods
Locations (3)
Guys' and St Thomas' Hospital NHS Trust
London, United Kingdom
Kings' College London Healthcare Trust
London, United Kingdom
Imperial College London Healthcare Trust
London, United Kingdom