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Lidocaine Versus Bupivacaine in Orthognathic Surgery
Sponsor: Boston Children's Hospital
Summary
In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery. Both anesthetics are within the standard of care for dental and orthognathic procedures, but can vary in how quickly they take action and how long they last. This study will provide us with a greater understanding of how anesthetic choice affect patient outcomes, and how we can strive to make these outcomes as favorable as possible.
Official title: Lidocaine Versus Bupivacaine in Orthognathic Surgery: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
15 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2024-10-01
Completion Date
2025-11-30
Last Updated
2026-08-04
Healthy Volunteers
Yes
Interventions
10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine
Injection of 10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine.
6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine
Injection of 6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine.
Locations (1)
Boston Children's Hospital
Boston, Massachusetts, United States