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Non-invasive Detection of Volatile Metabolites in Parkinson's Disease
Sponsor: Imperial College London
Summary
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Currently, a diagnostic test for early PD does not exist. The aim to address this problem by developing a non-invasive breath test to differentiate early PD from controls. Small molecules contained in breath, which offers precious information about disease presence, will be analysed. Data from the breath molecules and gut bacterial changes occurring in PD will be combined. These bacterial changes have been shown to arise years before the development of PD symptoms. Thanks to earlier diagnosis, therapies could start in advance and improve clinical outcomes and quality of life.
Official title: PArkinson's Non-Invasive Volatile ORganic Compound Analysis and Microbiome Assessment (PANORAMA) Study
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
OBSERVATIONAL
Enrollment
120
Start Date
2023-01-25
Completion Date
2025-01-30
Last Updated
2024-06-13
Healthy Volunteers
Yes
Conditions
Locations (1)
Charing Cross Hospital, Imperial College London
London, United Kingdom