Clinical Research Directory

Inclusion Criteria: 1. Patients with severe AECOPD.; 2. Age 40-80 years old; 3. Chinese medicine diagnosis consistent with external cold and internal drink syndrome, or phlegm-heat congestion of the lungs syndrome, or phlegm turbidity obstruction of the lungs syndrome; 4. Voluntarily accept the treatment and sign the informed consent form; Exclusion Criteria: 1. Pregnant and lactating women. 2. delirious, dementia, various mental patients and other people who cannot communicate normally. 3. Patients with severe cardiac insufficiency (NYHA grade IV), malignant arrhythmia and hemodynamic instability. 4. Patients with acute respiratory failure who require tracheal intubation or invasive mechanical ventilation. 5. Complicated with bronchiectasis, active tuberculosis, severe liver and kidney disease (severe liver disease refers to cirrhosis, portal hypertension and varicose vein bleeding, etc., serious kidney disease including dialysis, kidney transplantation, etc.), pneumonia, HIV infection or immunosuppressive state, advanced malignant tumor, etc. 6. long-term bedridden patients for various reasons. 7. Out-of-hospital treatment for more than 3 days. 8. Participate in other drug clinical investigators within 1 month before enrollment. 9. Allergic to therapeutic drugs.