Clinical Research Directory
Browse clinical research sites, groups, and studies.
What Laxative Should be Used After Hip Fracture Surgery?
Sponsor: Odense University Hospital
Summary
To conduct a randomized clinical trial to determine how best to prevent constipation after hip fracture surgery using laxatives.
Official title: Oral Laxatives After Hip Fracture Surgery: A Randomised Controlled Trial
Key Details
Gender
All
Age Range
65 Years - 110 Years
Study Type
INTERVENTIONAL
Enrollment
375
Start Date
2024-10-07
Completion Date
2027-01-31
Last Updated
2025-07-31
Healthy Volunteers
No
Conditions
Interventions
Bisacodyl
The patients' stool frequency, degree of constipation and side effects of the medication as well as pain, nausea and flatulence are scored once a day using the Bristol Stool Scale, Verbal Rank Scale and Patient Assessment of Constipation symptoms Questionnaire. If the first defecation has not occurred 72 hours after the end of the operation, the patients in all three groups are transferred to treatment with peristaltic-promoting agents
Macrogol 3350 and electrolytes
The patients' stool frequency, degree of constipation and side effects of the medication as well as pain, nausea and flatulence are scored once a day using the Bristol Stool Scale, Verbal Rank Scale and Patient Assessment of Constipation symptoms Questionnaire. If the first defecation has not occurred 72 hours after the end of the operation, the patients in all three groups are transferred to treatment with peristaltic-promoting agents
A combination of macrogol 3350 and electrolytes and bisacodyl
The patients' stool frequency, degree of constipation and side effects of the medication as well as pain, nausea and flatulence are scored once a day using the Bristol Stool Scale, Verbal Rank Scale and Patient Assessment of Constipation symptoms Questionnaire. If the first defecation has not occurred 72 hours after the end of the operation, the patients in all three groups are transferred to treatment with peristaltic-promoting agents
Locations (2)
Hospital Lillebælt, Kolding Hospital
Kolding, Denmark
Odense University Hospital, Svendborg Hospital
Svendborg, Denmark