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Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Sponsor: Kenyatta National Hospital
Summary
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and middle-income countries. Several evidence-based interventions are recommended for identification and management of PMAD by non-specialist providers in resource-limited settings. This cluster-randomized trial seeks to evaluate the effect of a stepped-care intervention for screening and treatment of PMAD among perinatal women, on clinical and implementation outcomes.
Key Details
Gender
FEMALE
Age Range
14 Years - Any
Study Type
INTERVENTIONAL
Enrollment
2970
Start Date
2025-02-17
Completion Date
2028-03
Last Updated
2025-12-10
Healthy Volunteers
Yes
Interventions
Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
The intervention includes systematic screening for PMAD symptoms using PHQ-2 and GAD-2, non-specialist delivery of PM+ for participants with likely depression (PHQ-9≥10) or anxiety (GAD-7≥10) and in-facility tele-linkage to mental health specialist for participants with severe depressive symptoms (PHQ-9≥15), those who endorse suicidality, or non-responders to PM+
Locations (2)
Kenyatta National Hospital
Nairobi, Kenya
HomaBay, Siaya and Kisumu
Western Kenya, Kenya