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ACTIVE NOT RECRUITING
NCT06456424
PHASE1/PHASE2

Bacteriophage Therapy for Methicillin-Sensitive Staphylococcus Aureus Prosthetic Joint Infection

Sponsor: University of Calgary

View on ClinicalTrials.gov

Summary

This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage cocktail to treat and prevent the recurrence of a methicillin-susceptible Staphylococcus aureus prosthetic joint infection of the hip. The patient has exhausted all conventional therapies, both surgical and medical, at considerable detriment to his quality of life. The treatment involves a one time, intra-operative injection of bacteriophages into the joint and 14 days of intravenous phage therapy. The goal is to eliminate the infection and prevent further complications, providing a potential new treatment avenue for patients with difficult-to-treat infections.

Key Details

Gender

MALE

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

1

Start Date

2024-11-20

Completion Date

2025-11

Last Updated

2025-06-11

Healthy Volunteers

No

Interventions

BIOLOGICAL

Phage therapy

Bacteriophage cocktail consisting of phages BP13 and J1P3

Locations (1)

South Health Campus

Calgary, Alberta, Canada