Clinical Research Directory

Inclusion Criteria: * Individuals with a unilateral transtibial amputation, divided into two groups (with and without diabetes) * Participants must classify as Medicare class K2 or higher (who can traverse low-level environmental barriers such as curbs, stairs or uneven surfaces). * Participants must have undergone amputation at least 6 months prior. * They must have the ability to walk for at least 10 continuous minutes without undue fatigue. Exclusion Criteria: * Neurological impairment that may affect walking function, such as stroke, severe traumatic brain injury, Parkinson's disease, and multiple sclerosis. * History of inflammatory diseases, such as Raynaud's syndrome or rheumatoid arthritis.