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RECRUITING
NCT06458504

Viral Infection of HSPC Impacts Hematopoiesis

Sponsor: Assistance Publique - Hôpitaux de Paris

View on ClinicalTrials.gov

Summary

We propose to demonstrate that HIV-1 and SARS-CoV-2 are capable of targeting long-lived HSPC with self-renewal capacities. These progenitors, thus transformed into host cells, can give rise to a durable source of infected cells with an impact on hematopoiesis.

Official title: Virus-induced Immunosuppression Via Infection of Hematopoietic Progenitors

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

45

Start Date

2024-10-25

Completion Date

2026-03

Last Updated

2025-03-20

Healthy Volunteers

No

Conditions

Locations (1)

Hematology and interne medicine department, Ambroise Paré hospital - APHP

Boulogne-Billancourt, France