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RECRUITING
NCT06462040

Evaluation of Clinical and Radiological Outcomes in Patients Undergoing Fixation of Osteochondral Fragments With Reasorbable Screws in the Knee Joint

Sponsor: Istituto Ortopedico Rizzoli

View on ClinicalTrials.gov

Summary

Various techniques for the fixation of unstable osteochondral fragments have been used over the years, each with associated advantages and disadvantages, and differing clinical outcomes. However, the literature on the treatment of this type of injury in the adolescent and young adult population is scarce and involves small case series. Failure to treat these injuries can lead to serious consequences such as chronic pain, residual joint stiffness, and the development of early osteoarthritis, necessitating more invasive and burdensome interventions for the national health system, such as prosthetic replacements or osteotomies. Due to the lack of real consensus within the scientific community regarding the ideal treatment for these patients and the insufficient medium/long-term follow-up data on the effects of these injuries on articular cartilage in young patients, this study aims to evaluate the clinical and radiological conditions of patients undergoing osteochondral fragment fixation using the same surgical technique (fixation with resorbable screws performed arthroscopically or via open surgery depending on the lesion's location) in order to clarify preventive measures against cartilage degeneration following these injuries, which are very common in adolescence.

Key Details

Gender

All

Age Range

12 Years - 35 Years

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2024-09-25

Completion Date

2028-06

Last Updated

2026-01-30

Healthy Volunteers

No

Interventions

PROCEDURE

Fixation of osteochdral fragments with reabsorbable screws

Arthroscopic or mini-open fixation of free-intrarticular or unstable osteochondral fragments due to osteochondritis dissecans or osteochondral fractures with reabsorbable screws

Locations (1)

IRCCS Rizzoli Orthopedic Institute

Bologna, Bologna, Italy