Clinical Research Directory
Browse clinical research sites, groups, and studies.
Association Between Serum and Neuroimaging Measurements of the GABAergic System
Sponsor: Francois Corbin
Summary
The goal of this study is to better understand the relationship between peripheral and central nervous system measurements of the gamma-aminobutyric acid (GABA) system in otherwise healthy individuals. the main questions it aims to answer are: 1. Does GABA cross the blood-brain barrier? 2. Can peripheral measurements of the GABAergic system be used to study GABA in the brain? Participants will receive oral GABA and Placebo and undergo blood draws, MRI scans and transcranial magnetic stimulation sessions.
Official title: The GABAergic System: Study of the Association Between Serum Measurements and Those Obtained Through Neuroimaging in Healthy Human Adults
Key Details
Gender
All
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2025-05-05
Completion Date
2026-07-01
Last Updated
2025-02-17
Healthy Volunteers
Yes
Conditions
Interventions
Acute Oral gamma-aminobutyric acid (Natural Health Product in Canada)
1800 mg (3 capsules of 600mg) of GABA taken at the research center under the supervision of the research team.
Acute Placebo
A capsule filled with powdered sugar taken under the supervision of the research team.