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NOT YET RECRUITING
NCT06466005

UnityPhilly Response App for Overdose Reversal

Sponsor: Drexel University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to discover if an overdose prevention app (UnityPhilly) can encourage citizen responders to respond and prevent opioid overdoses using the UnityPhilly app. The main hypotheses to answer are: Hypothesis 1: UnityPhilly signal rates relative to EMS calls will increase over time. The primary outcome will be assessed as the total number of overdoses signaled by participants relative to all overdose-related EMS calls, per year. Hypothesis 2: The number of cases where a nearby UnityPhilly participant successfully reverses an overdose with naloxone will increase over time. The primary outcome will be assessed as the number of successful reversals relative to the total number of responder arrivals, per year. Participants will be supplied with the UnityPhilly app, training on how to use the app and respond to an opioid overdose using naloxone, and respond to follow up surveys about their experiences.

Official title: UnityPhilly Response App for Overdose Reversal: Assessing Citywide Effectiveness and Sustainability

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

450

Start Date

2025-08-01

Completion Date

2028-07

Last Updated

2025-06-17

Healthy Volunteers

Yes

Conditions

Interventions

OTHER

UnityPhilly app

UnityPhilly automatically connects bystanders and victims of opioid overdose with nearby community members who can respond immediately with naloxone.

Locations (1)

Drexel University

Philadelphia, Pennsylvania, United States