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Speech Motor Learning and Retention (Master Protocol)
Sponsor: Yale University
Summary
The overall goal of this research is to test a new model of speech motor learning, whose central hypothesis is that learning and retention are associated with plasticity not only in motor areas of the brain but in auditory and somatosensory regions as well.
Official title: Sensorimotor Basis of Speech Motor Learning and Retention
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
330
Start Date
2024-10-01
Completion Date
2029-05-31
Last Updated
2026-02-19
Healthy Volunteers
Yes
Conditions
Interventions
continuous theta-burst stimulation (cTBS)
cTBS stimulation will be applied to different areas of the brain following learning. Stimulation will take place following learning in order to block motor memory retention.
Adaptation
Auditory adaptation in speech
Single pulse Transcranial magnetic stimulation (TMS)
TMS will be delivered 10 times in each motor evoked potentials (MEP) recording block.
fMRI
To assess functional connectivity patterns between regions that predict learning.
Locations (1)
Yale Child Study Center
New Haven, Connecticut, United States