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Novel Augmentation of DAOIB and Antioxidant for Early Dementia
Sponsor: Chang Gung Memorial Hospital
Summary
Previous studies found that some NMDA-enhancing agents were able to improve cognitive function of patients with early-phase dementia. In addition, several drugs with antioxidant properties have been tested in clinical trials for the treatment of dementia too. Whether combined treatment of an NMDA-enhancing agent and a drug with antioxidant property can be better than an NMDA-enhancing agent alone deserves study.
Key Details
Gender
All
Age Range
50 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2024-06-19
Completion Date
2027-05
Last Updated
2026-03-19
Healthy Volunteers
No
Interventions
DAOIB plus AO
oral, for 24 weeks
DAOIB plus placebo
oral, for 24 weeks
Locations (1)
Chang Gung Memorial Hospital
Kaohsiung City, Taiwan