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RECRUITING
NCT06467695
NA

Low Voltage Electrical Stimulation for Depression in Parkinson's Patients

Sponsor: University of South Alabama

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to determine the relative efficacy of fMRI model guided Transcranial Direct Current Stimulation (mgTDCS) in improving the depressive symptoms of patients with Parkinson's Disease (PD). The main questions it aims to answer are: 1) Can the use of mgTDCS significantly improve the self-reported level of depression and apathy in patients with PD from pre-intervention to post-intervention compared to a sham control? 2) Can the use of mgTDCS significantly normalize the cortical eeg alpha asymmetry so commonly seen in depressed patients compared to sham mgTDCS? 3) Can the use of mgTDCS significantly improve scores on neuropsychological tests of working memory?

Official title: The Effect of MRI-Guided Transcranial Direct Current Stimulation on Cognitive and Affective Symptoms in Persons With Parkinson's Disease and Controls

Key Details

Gender

All

Age Range

19 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2024-08-01

Completion Date

2027-06-30

Last Updated

2026-04-06

Healthy Volunteers

No

Interventions

DEVICE

BIOPAC Stimsola

Transcranial Electrical Stimulator

DEVICE

BIOPAC Stimsola Sham (zero amps)

Transcranial Electrical Stimulator set to 0 amps

Locations (1)

University of South Alabama

Mobile, Alabama, United States