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Low Voltage Electrical Stimulation for Depression in Parkinson's Patients
Sponsor: University of South Alabama
Summary
The goal of this clinical trial is to determine the relative efficacy of fMRI model guided Transcranial Direct Current Stimulation (mgTDCS) in improving the depressive symptoms of patients with Parkinson's Disease (PD). The main questions it aims to answer are: 1) Can the use of mgTDCS significantly improve the self-reported level of depression and apathy in patients with PD from pre-intervention to post-intervention compared to a sham control? 2) Can the use of mgTDCS significantly normalize the cortical eeg alpha asymmetry so commonly seen in depressed patients compared to sham mgTDCS? 3) Can the use of mgTDCS significantly improve scores on neuropsychological tests of working memory?
Official title: The Effect of MRI-Guided Transcranial Direct Current Stimulation on Cognitive and Affective Symptoms in Persons With Parkinson's Disease and Controls
Key Details
Gender
All
Age Range
19 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-08-01
Completion Date
2027-06-30
Last Updated
2026-04-06
Healthy Volunteers
No
Conditions
Interventions
BIOPAC Stimsola
Transcranial Electrical Stimulator
BIOPAC Stimsola Sham (zero amps)
Transcranial Electrical Stimulator set to 0 amps
Locations (1)
University of South Alabama
Mobile, Alabama, United States