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RECRUITING
NCT06468124

Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases

Sponsor: King's College London

View on ClinicalTrials.gov

Summary

The aim of the study is to generate patient-derived organoids (PDOs) from brain resection or biopsied extra-cranial metastases. The preliminary data collected will be used to assess the ability of PDOs to predict patients' treatment response and their radio-sensitivity and chemo-sensitivity can be correlated with their survival outcome.

Official title: Prospective Study to Correlate the Treatment Sensitivity of Patient-derived Organoids With Clinical Outcomes in Breast Cancer Patients With Brain and/or Extra-cranial Metastases

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

20

Start Date

2025-05-27

Completion Date

2026-06-30

Last Updated

2025-12-22

Healthy Volunteers

No

Locations (2)

Guy's and St. Thomas NHS Foundation Trust

London, United Kingdom

King's College Hospital NHS Foundation Trust

London, United Kingdom