Clinical Research Directory

Inclusion Criteria: * Aged 50 years or older. * Willing and able to comply with all study requirements and visits. * Provided written informed consent. Study Eye: * Recent onset as demonstrated by symptoms or diagnosis macular involving rhegmatogenous retinal detachment. * Detachment due to single or multiple retinal tears in the superior region of the retina Fellow eye: • Visual acuity of 6/12 or better. Exclusion Criteria: * History of medical, surgical, or other conditions that, in the opinion of the investigator, would limit study participation e.g. unstable diabetes, poorly controlled hypertension. * Travel limitations that could prevent review at proscribed study intervals or any other time during the study. * Inability to provide informed consent. * Anaesthetic risk factors or inability to lie supine for 1 hour. * Pregnant and/or breast feeding (to be confirmed on treatment day) * Current systemic infection * Current ocular infection * Unable to return for post-treatment visits * Known inability to attend the emergency department in the event of an adverse event. Exclusion criteria in the study eye: * Significant vitreous haemorrhage partially or fully obscuring detailed examination of the retina * Intraoperative identification of tears below the superior region in the area of retinal detachment not identified at the screening visit or during pre-operative examination. Note: Isolated retinal tears in attached retina, identified at any time are NOT an exclusion criterion and may be treated with lase as per standard of care * Clinical signs of PVR (+1 flare, vitreous clumps, pigment clusters on the inferior retina, rolled retinal tear edge, star-fold) * Myopia greater than -4 D spherical equivalent as confirmed by last refraction prior to becoming pseudophakic if cataract surgery has been performed * History of glaucoma or elevated intraocular pressure \>21mmHg * Prior or current intraocular infection Exclusion criteria in the fellow eye: * Visual Acuity worse than 6/12 * Myopia greater than -4D spherical equivalent or axial length greater than 26mm if known * Any potential sight threatening pathology in the fellow eye as determined by the investigator * Extensive lattice degeneration * Unilateral high myopia as determined by the investigator * Family history of retinal detachment * Collagen disorders such as Marfan's or Sticklers syndrome * History of ocular trauma * Evidence of any abnormality of the eye structure as determined by the investigator * Planned surgery during the study period