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Deep Neuromuscular Block Affect the Quality of Recovery After Laparoscopic Hysterectomy
Sponsor: Anqing Municipal Hospital
Summary
BACKGROUND: Some studies have revealed that deep neuromuscular block (NMB) improve surgical conditions and alleviated postoperative pain compared with moderate NMB. The present study investigated deep NMB could improve the quality of recovery after laparoscopic hysterectomy METHODS: seventy-two women with elective laparoscopic hysterectomy were randomly divided into 2 groups: Patients in group A received low-pressure pneumoperitoneum (LPP), which was set at 8-10 mmHg with deep NMB. Patients in group B received standard-pressure pneumoperitoneum (SPP), which was set at 12-14 mmHg with moderate NMB. Primary outcome was the quality of recovery (QoR-15) at 1 day after sugery. The secondary outcomes included postoperative pain, surgical condition, incidence of shoulder pain, the incidence of rescue analgesic drug use, cumulative dose of analgesics, time of first flatus, post-operative nausea and vomiting, time of tracheal tube removal.
Official title: Effect of Deep Neuromuscular Block on the Quality of Recovery After Laparoscopic Hysterectomy
Key Details
Gender
FEMALE
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2024-06-25
Completion Date
2024-11-25
Last Updated
2024-06-24
Healthy Volunteers
No
Conditions
Interventions
low-pressure pneumoperitoneum
low-pressure pneumoperitoneum (LPP) with deep NMB.
standard-pressure pneumoperitoneum
standard-pressure pneumoperitoneum (SPP) with moderate NMB.
Locations (1)
Department of Anqing Munucipal Hospital Anesthesiology
Anqing, Anhui, China