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Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults
Sponsor: Centre Hospitalier Régional Metz-Thionville
Summary
This is a prospective, observational, monocentric, phase II (exploratory) cohort study aiming to describe the evolutionary profile of the initial volume of glucose distribution (IDVG) during the first four days of management of severely burned patient.
Official title: INDICIA: Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2024-11-28
Completion Date
2027-03-28
Last Updated
2026-03-12
Healthy Volunteers
No
Conditions
Interventions
Glucose 30% Intravenous Solution
Measurement of IDVG on admission, at 4 hours (H+4), and at 8, 16, 24, 48, 72 and 96 hours (H+8, H+16, H+24, H+48, H+72 and H+96) post-burn. The principle of this measurement consists of taking a reference blood glucose level measured on an arterial blood sample (arterial catheter) using a blood glucose meter. A bolus of 5g of glucose is injected into a central venous line over 30 seconds. A second blood glucose level is measured 3 minutes after the end of the injection. The intra-thoracic blood volume (ITBV) and extra-vascular lung water (EVLW) are measured using the PiCCO device as part of the usual management of burn patients.
Locations (1)
CHR Metz-Thionville/Hopital de Mercy
Metz, France