Clinical Research Directory

Inclusion Criteria: 1. Men and women ≥ 18 and \< 85 years of age with a diagnosis ischemic or hemorrhagic stroke at \> 6 months since stroke onset event. 2. FMA-LE scores \< 34 at screening with residual paresis in the lower extremity. 3. Able to walk at least 10 feet with or without assistive device. 4. FGA score \< 23 at screening. 5. Montreal Cognitive Assessment 5-min (MoCA 5-min) ≥ 6 6. Able to understand, learn and apply instructions on how to operate the PoNS device and perform the rehabilitation exercise program. Exclusion Criteria: 1. Pre-existing neurological disorders or previous stroke affecting the other hemisphere. 2. Severe arthritis or orthopedic problems that limit passive range of motion. 3. Areas of recent bleeding or open wounds; or areas that lack normal sensation on the tongue. 4. Diagnosis of dementia or mild cognitive impairment 5. Concurrent daily use of transcutaneous electric nerve stimulation (TENS) and/or other peripheral stimulation devices (i.e. Bioness®) 6. Neurostimulation therapy over the previous 6 months 7. Cancer treatment within the past year. 8. Nonremovable metal orthodontic devices. 9. Oral health problems. 10. Chronic infectious diseases. 11. Pregnancy. 12. Sensitivity to nickel, gold or copper.