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RECRUITING
NCT06470321
NA

Biopsychosocial Predictors of Nicotine Relapse

Sponsor: University of Cyprus

View on ClinicalTrials.gov

Summary

This study aims to investigate the associations between emotion regulation ability, stress-induced neural activity changes, and susceptibility to relapse in smokers attempting to quit. Participants will undergo assessments of emotion regulation, neural activity via quantitative electroencephalography (qEEG), and stress responses before and during a 24-hour nicotine abstinence period. They will then participate in a computerized smoking cessation intervention, and their abstinence status will be monitored for 6 months.

Official title: Identifying Biomarkers of Stress-induced Neurophysiological Changes and Emotion Regulation Deficits to Predict Relapse During Nicotine Abstinence

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2022-01-01

Completion Date

2025-05-01

Last Updated

2024-06-24

Healthy Volunteers

No

Interventions

BEHAVIORAL

Flexiquit Computerized Smoking Cessation Program

Flexiquit is an avatar-led, self-directed computerized program delivering evidence-based techniques to assist with smoking cessation. It includes motivational interviewing, psychoeducation on nicotine addiction, cognitive-behavioral strategies for coping with cravings, relapse prevention, and stress/emotion regulation skills training. Participants receive the program over 6 months and their adherence is monitored. The program provides tailored feedback to support abstinence.

Locations (1)

Center for Applied Neuroscience

Nicosia, Cyprus