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Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies
Sponsor: University of Cyprus
Summary
This case-control study aims to investigate the genetic and molecular bases of nicotine addiction to identify potential therapeutic targets. The project will involve drug repurposing using Mendelian Randomization, a smoking cessation intervention, and the analysis of methylation status in participants undergoing nicotine withdrawal.
Official title: Exploring the Genetic and Molecular Underpinning of Nicotine Addiction for the Development of New Therapeutic Strategies
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2023-11-01
Completion Date
2025-10-31
Last Updated
2024-06-25
Healthy Volunteers
No
Conditions
Interventions
Flexiquit Smoking Cessation Intervention
Participants will enter a 6-week (once weekly) self-delivered computerized intervention program called Flexiquit. Developed and validated by Clinical Psychologists of the Department of Psychology at the University of Cyprus, Flexiquit is an avatar-led app designed to support smoking cessation. It aims to assist with abstinence and monitor participants' progress through personalized modules and assessments.
Locations (1)
Center for Applied Neuroscience (CAN)
Nicosia, Cyprus