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COMPLETED
NCT06471647
EARLY_PHASE1

Effects of Drugs on Stress Memories

Sponsor: University of Chicago

View on ClinicalTrials.gov

Summary

There is evidence that cannabinoids, including delta-9-tetrahydrocannabinol (THC), reduce responses to acute stress and fear-related stimuli, but few studies have examined the effects of THC on memories of stressful experiences. The researchers hypothesize that THC will attenuate behavioral and physiological responses to negative valence stimuli, including memories of aversive experiences.

Key Details

Gender

All

Age Range

18 Years - 35 Years

Study Type

INTERVENTIONAL

Enrollment

36

Start Date

2024-07-01

Completion Date

2025-03-25

Last Updated

2026-07-09

Healthy Volunteers

Yes

Interventions

DRUG

delta-9-tetrahydrocannabinol (THC) (5)

5 mg of THC

DRUG

Placebo

Placebo - dextrose

DRUG

delta-9-tetrahydrocannabinol (THC) (10)

10 mg of THC

Locations (1)

University of Chicago

Chicago, Illinois, United States