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ENROLLING BY INVITATION
NCT06472362

Chest CT Biomarkers as Prognostic Predictors in SSc-ILD

Sponsor: Royal Brompton & Harefield NHS Foundation Trust

View on ClinicalTrials.gov

Summary

The goal of this retrospective observational study is to investigate whether novel imaging biomarkers of airways, vessels, and overall extent of fibrosis at baseline predict ILD progression, vasculopathy development, and survival in SSc-ILD.

Official title: Deep-learning Derived Chest Computed Tomography (CT) Biomarkers as Prognostic Predictors in Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)

Key Details

Gender

All

Age Range

18 Years - 99 Years

Study Type

OBSERVATIONAL

Enrollment

1000

Start Date

2024-11-01

Completion Date

2026-03-31

Last Updated

2025-09-11

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

HRCT biomarkers

HRCT imaging biomarkers of airways, vessels, and overall extent of fibrosis

Locations (7)

Bichat-Claude Bernard hospital

Paris, France

Hanover Medical School

Hanover, Germany

Marche Polytechnic University

Ancona, Italy

Sassari University

Sassari, Italy

Siena University Hospital

Siena, Italy

Leeds Hospital/University of Leeds

Leeds, United Kingdom

Royal Brompton Hospital

London, United Kingdom