Clinical Research Directory

Inclusion Criteria: * Out-of-hospital cardiac arrest with stable return of spontaneous circulation (ROSC \> 20 minutes) * Patient receiving invasive mechanical ventilation for coma (Glasgow score \< 8) * Availability of a lower limb without intravenous infusion or tension cuff positioned on it * Randomization and application of the first session of the tested procedure within 4 hours after ROSC * Consent of a next-of-kin or inclusion in emergency procedure Exclusion criteria : * Age \< 18 y.o or pregnancy * Patient unable to walk without assistance, unable to support himself properly without assistance, bedridden, incontinent and requiring nursing constant attention and care (corresponding to a mRS equal to 4 or 5) * Interval between cardiac arrest and ROSC (no flow + low flow) estimated \> 60 minutes * Unwitnessed cardiac arrest with asystole as first rhythm * In-hospital cardiac arrest * Refractory cardiac arrest (no ROSC considered as stable) * Cardiac arrest from traumatic, hemorrhage, stroke or hanging supposed origin * Mean arterial pressure \< 65mmHg persisting despite appropriate vascular filling and vasopressor and/or inotropic support * Active uncontrolled bleeding * Contraindication or not possible to use a pneumatic tourniquet on none of the two lower limbs (amputations, intravenous infusion positioned on both lower limbs, tourniquet size incompatible with patient morphology) * Implementation of extracorporeal arteriovenous circulation for refractory cardiac arrest or refractory cardiogenic shock before inclusion * Patient already included in this study * Inclusion in another interventional study * Judicial protection measure * Patient without French social security