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ACTIVE NOT RECRUITING
NCT06473506
NA

Group A Streptococcus Saliva Study

Sponsor: The Hospital for Sick Children

View on ClinicalTrials.gov

Summary

This study is being done to evaluate whether saliva can be used to diagnose GAS infection and also to compare different testing methods in the microbiology lab. The saliva sample testing will be compared to the throat swab testing to see if saliva testing works as well. The lab will also try different testing methods to see if a faster type of testing (e.g. molecular testing) works as well as the regular method, which takes 48 hours to get results. This is important because throat swabs can be challenging to collect in some children, and saliva is often much easier and more acceptable by children to collect. This could improve our ability to accurately diagnose and treat GAS infections.

Official title: Exploring the Use of Saliva for the Detection of Group A Streptococcus

Key Details

Gender

All

Age Range

0 Years - 18 Years

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2024-06-10

Completion Date

2026-04-30

Last Updated

2025-11-26

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Saliva collection

Self-collected saliva sample with molecular testing performed. Results are compared to rapid antigen testing, bacterial throat culture and bacterial throat molecular testing

Locations (2)

Monica Caldeira-Kulbakas

Toronto, Ontario, Canada

The Hospital for Sick Children

Toronto, Ontario, Canada