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Group A Streptococcus Saliva Study
Sponsor: The Hospital for Sick Children
Summary
This study is being done to evaluate whether saliva can be used to diagnose GAS infection and also to compare different testing methods in the microbiology lab. The saliva sample testing will be compared to the throat swab testing to see if saliva testing works as well. The lab will also try different testing methods to see if a faster type of testing (e.g. molecular testing) works as well as the regular method, which takes 48 hours to get results. This is important because throat swabs can be challenging to collect in some children, and saliva is often much easier and more acceptable by children to collect. This could improve our ability to accurately diagnose and treat GAS infections.
Official title: Exploring the Use of Saliva for the Detection of Group A Streptococcus
Key Details
Gender
All
Age Range
0 Years - 18 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2024-06-10
Completion Date
2026-04-30
Last Updated
2025-11-26
Healthy Volunteers
No
Conditions
Interventions
Saliva collection
Self-collected saliva sample with molecular testing performed. Results are compared to rapid antigen testing, bacterial throat culture and bacterial throat molecular testing
Locations (2)
Monica Caldeira-Kulbakas
Toronto, Ontario, Canada
The Hospital for Sick Children
Toronto, Ontario, Canada