Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Following Treatment With Remifentanil
Sponsor: Assaf-Harofeh Medical Center
Summary
Analgesia is one of the pillars of anesthesia. One of the common opiates for pain relief, with a short half-life, is Remifentanil. However, following Remifentanil treatment an increased sensitivity to pain \[hyperalgesia\] appears. The aim of the study is to compare the effects between complementary treatments, like Ketalar and Dexmedetomidine, in preventing increased sensitivity to pain after Remifentanil treatment
Official title: Comparison of the Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Induced Following Treatment With Remifentanil in Patients Undergoing a Laparoscopic Cholecystectomy
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2024-04-18
Completion Date
2026-08-30
Last Updated
2024-08-07
Healthy Volunteers
No
Conditions
Interventions
Ketalar
a dissociative anesthetic used medically for induction and maintenance of anesthesia
Dexmedetomidine
an agonist of α2-adrenergic receptors in certain parts of the brain used for sedation
Locations (1)
Shamir (Asaf Harofe) Medical Center
Be’er Ya‘aqov, Israel