Clinical Research Directory

Inclusion Criteria: * 1\. Adult women aged 18-75 years old * 2\. First-time referral to the breast clinic or inpatient department of the study center for being diagnosed as presenting with suspicious breast lesions by previous procedures in 30 days * 3\. Presenting with Index lesions of "BI-RADS≥4" and additional findings in preoperative breast MRI * 4\. Sign the informed consent form for this study. * 5\. Commit to follow the research procedures and cooperate with the implementation of the whole process of the study. * 6\. In the case of women of childbearing age, have been taken contraception for at least one month prior to screening and have had a negative serum or urine pregnancy test and commit to use contraception throughout the study period Exclusion Criteria: * 1\. Patients with contraindications of intravenous administration of iodine contrast agent, such as pregnant or lactating women, patients with a history of iodine contrast agent allergy, patients with obvious hyperthyroidism * 2\. It has been more than 14 days since the most recent preoperative breast MRI was performed for the relevant breast disease * 3\. For the relevant breast disease, the preoperative breast MRI images and reports received within 14 days before screening are not available or do not meet the requirements of clinical diagnosis * 4\. Patients who is receiving non-surgical interventional treatment such as neoadjuvant chemotherapy, hormone therapy or radiation therapy * 5\. Patients who have received any breast operation for the relevant disease, such as various biopsies, therapeutic breast surgery * 6\. Other patients assessed by the investigators as not suitable for the study, such as those who are difficult to cooperate with CESM examination due to unconsciousness, communication disorder or/and small breasts to meet the examination requirements