Clinical Research Directory

Inclusion Criteria: * Age 18-65 years old * Meet the criteria for impaired glucose regulation according to the "Guidelines for the Prevention and Treatment of Type 2 Diabetes in China (2020 Edition)": IFG: Fasting blood glucose ≥ 6.1 mmol/L and \< 7.0 mmol/L IGT: 2-hour postprandial glucose ≥ 7.8 mmol/L and \< 11.1 mmol/L * Meet the Asia-Pacific criteria for overweight and obesity: 23 kg/m2 ≤ BMI * Signed informed consent Exclusion Criteria: * Patients diagnosed with diabetes or currently undergoing diabetes treatment * Patients who have received weight loss medication or surgery in the past 3 months * Patients who are taking corticosteroids or thyroid hormones * Patients with secondary obesity caused by endocrine, genetic, metabolic, or central nervous system diseases * Patients with severe liver function or abnormal kidney function * Patients with diseases that affect food digestion and absorption * Patients with cardiovascular diseases, grade 3 hypertension, chronic hepatitis, malignant tumors, anemia, mental illness and memory disorders, epilepsy, etc. * Patients with active tuberculosis, AIDS, and other infectious diseases * Pregnant or breastfeeding women * Patients with limb disabilities or other conditions that the clinical investigator deems inappropriate for participation in the study.