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Predicting Early Tumor Recurrence in Patients With Esophageal Squamous Cell Carcinoma
Sponsor: City of Hope Medical Center
Summary
The prognosis of patients with esophageal squamous cell carcinoma (ESCC) who develop post-operative early tumor recurrence is often relatively poor. Therefore, biomarker that can detect micro metastases before the start of treatment is required. Epigenomic alterations such as DNA methylation have attracted attention as promising biomarkers. The investigators aim to predict early recurrence based on whole genome DNA methylation analysis of esophageal cancer.
Official title: Predicting Postoperative Early Tumor Recurrence in Patients With Esophageal Squamous Cell Carcinoma
Key Details
Gender
All
Age Range
20 Years - Any
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2006-01-01
Completion Date
2026-06-18
Last Updated
2025-07-11
Healthy Volunteers
Not specified
Interventions
Surgery
Esophagectomy
Locations (2)
Nagoya University
Nagoya, Aichi-ken, Japan
Yamanashi Universiy
Chūō, Yamanashi, Japan