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Study of Preoperative RAdiation Therapy With Concomitant Liposomal Transcrocetin (L-TC) in Soft tISsue Sarcomas
Sponsor: Institut de cancérologie Strasbourg Europe
Summary
This is phase II randomized, multicenter study of treatment with L-TC and preoperative HFRT in patients who were aged 18 years or older with documented localised or locally advanced soft-tissue sarcoma of the extremity. Eligible patients will be randomly assigned 2:1 to receive a preoperative HFRT alone (Arm A) or L-TC with preoperative HFRT (Arm B).
Official title: Phase 2 Study of Preoperative RAdiation Therapy With Concomitant Liposomal Transcrocetin (L-TC) in Soft tISsue Sarcomas
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
42
Start Date
2025-06-01
Completion Date
2032-06-01
Last Updated
2025-02-04
Healthy Volunteers
No
Conditions
Interventions
Administration of L-TC
Administration of L-TC (300 mg) as an IV perfusion, daily before each radiotion session
HFRT alone
HFRT : 30 Gy in 5 fractions of 6 Gy. 1 fraction per day, 5 days per week.
Locations (2)
CGFL
Dijon, France
ICANS
Strasbourg, France